Neuroprotective Effect of Betaxolol, Dorzolamide, Brimonidine and Ginkgo Biloba in Patients with Normal Tension Glaucoma
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منابع مشابه
Neuroprotection in Glaucoma
Glaucoma is a degenerative optic neuropathy characterized by retinal ganglion cell (RGC) loss and visual field defects. It is known that in some glaucoma patients, death of RGCs continues despite intraocular pressure (IOP) reduction. Neuroprotection in the field of glaucoma is defined as any treatment, independent of IOP reduction, which prevents RGC death. Glutamate antagonists, ginkgo biloba ...
متن کاملPatient persistency with pharmacotherapy in the management of glaucoma.
PURPOSE To evaluate persistency with monotherapy in the treatment of glaucoma in patients new to pharmacological management. METHODS This population-based, retrospective cohort study, using managed care administrative claims data, included patients who were 20 years of age and older and who initiated monotherapy with betaxolol, brimonidine, dorzolamide, latanoprost, or timolol between May 199...
متن کاملCurrent Preferred Agents: BETAXOLOL, BRIMONIDINE (ALPHAGAN AND ALPHAGAN P), BRINZOLAMIDE (AZOPT), CARTEOLOL. DORZOLAMIDE/TIMOLOL, LATANOPROST, PILOCARPINE GEL AND DROPS, and TRAVOPROST (TRAVATAN Z®). Current Non-preferred Agents: ACETAZOLAMIDE, ACETYLCHOLINE CHLORIDE (MIOCHOL-E), ALPHAGAN® P, ALPRACLONIDINE (IOPIDINE), AZOPT®, BETAXOLOL
Background: The first goal of medical therapy in glaucoma is to reduce intraocular pressure (IOP), and the fixed-combination medications are needed to achieve sufficiently low target IOP. The aim of this systematic review and meta-analysis is to evaluate IOP-lowering effect of the commonly used fixed-combination drugs containing 0.5% timolol. Methods: Pertinent publications were identified thro...
متن کاملNeuroprotection in Glaucoma
Glaucoma is a neurodegenerative disorder in which a variety of complicated mechanisms lead to retinal ganglion cell (RGC) apoptosis and death. According to various theories, factors including elevated intraocular pressure (IOP) and vascular dysregulation primarily contribute to the initial insult during glaucomatous atrophy in the form of obstruction of axoplasmic flow within RGC axons, alterat...
متن کاملShort-Term Effects of Ginkgo biloba Extract on Peripapillary Retinal Blood Flow in Normal Tension Glaucoma
PURPOSE Based on the vascular theory of glaucoma pathogenesis, we wanted to evaluate the effect of Ginkgo biloba extract (GBE) on peripapillary blood flow in patients with normal tension glaucoma (NTG). METHODS Thirty patients with NTG were randomly placed in the GBE-treated or control groups. The GBE-treated group received 80 mg GBE orally, twice a day for four weeks, and the control group r...
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